Month: April 2022

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 56413-95-7, is researched, Molecular C6Cl2N4, about Dually directional glycosylated phthalocyanines as extracellular red-emitting fluorescent probes, the main research direction is glycosylated phthalocyanine extracellular red emitting fluorescent probe.Formula: C6Cl2N4.

The development of new non-aggregated phthalocyanines bearing multivalent saccharide moieties on their macrocyclic rims is of great interest. Many characteristics, including water-solubility, non-toxicity and others, can be feasibly obtained by these amphiphiles which can be considered as a key solution for demonstrating highly efficient photoactive materials in water. Herein, a family of five newly prepared dually directional Zn(II) containing phthalocyanines (PcG1-4) and azaphthalocyanine (AzaPcG1) glycoconjugates is described. The unique spatial arrangement of the glucoside units based on peripherally hexadeca-(PcG1) and nonperipherally octa-(PcG4) macrocycles provides a fully monomeric behavior along with a high fluorescence (ΦF ~0.21) in aqueous solution These amphiphiles were characterized by low toxicity, and an extremely low cellular uptake was obtained due to the highly polar nature of the glucoside substituents. Accordingly, their potential as suitable photoactive chromophores for red-emitting extracellular fluorescent probes has been confirmed upon the evaluation of paracellular transport using a layer of MDCKII cells with the permeability coefficient fully comparable with an established evaluator of the integrity of the monolayer.

Here is just a brief introduction to this compound(56413-95-7)Formula: C6Cl2N4, more information about the compound(5,6-Dichloropyrazine-2,3-dicarbonitrile) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Pyrolysis studies. Controlled thermal degradation of mesoporphyrin》. Authors are Whitten, David G.; Bentley, Kenton E.; Kuwada, Daniel.The article about the compound:3-Methyl-1H-pyrrolecas:616-43-3,SMILESS:CC1=CNC=C1).Related Products of 616-43-3. Through the article, more information about this compound (cas:616-43-3) is conveyed.

The major organic products obtained from thermal decomposition of mesoporphyrin (I) at several temperatures over the range 400-780° were pyrrole, 3-methylpyrrole, dimethylpyrroles, trimethylpyrroles, opsopyrrole (II), cryptopyrrole (III), tetramethylpyrrole, hemopyrrole (IV), and phyllopyrrole (V). Small amounts of MeCN and EtCN were obtained together with moderate yields of CH4, C2H6, and C2H4. The yields of hydrocarbons and nitriles increased with the temperature Thermal decomposition products of I at lower temperatures (400-600°) were the same as those favored in reductive degradation. The pyrroles II-V, formed by cleavage at the methene bridge positions only amounted to 92% of alkylpyrroles formed at 410°. The yield of less characteristic pyrroles increased with elevation of the pyrolysis temperature Spectral examination of the residue failed to show any dipyrrylmethanes or rearranged porphyrins that might be possible intermediates in pyrrole formation. Increase of pyrolysis hot zone by use of a gold baffle caused a less characteristic pyrolysis above 550°. Above 560°, 2,4-dimethyl-3-ethylpyrrole (VI) gave considerable amounts of dimethylpyrrole and methylpyrrole. The products of sealed tube pyrolysis of I in vacuo and in H atm. (450-500 mm. at 20°) heated 1 hr. at 400° were the same as those produced by pyrolysis in dynamic systems at the same temperature Mass spectral determinations of VI and the isomer 2,3,4,5-tetramethyl-pyrrole show that the method served to distinguish between such pairs but not between isomers having the same types of alkyl substituents. The spectra of mesoporphyrin IX and ferric mesoporphyrin IX chloride di-Me ester as obtained using a direct introduction system were similar to previously reported spectra of Ni and Cu etioporphyrins. Relatively high stability of porphyrin pos. and double pos. ions gives rise to little fragmentation of the porphyrin nucleus. The high-resolution mass spectrum of I gives mol. weight and mol. formula, with a fragmentation pattern indicating high stability. Controlled pyrolysis selectivity degrades the porphyrin into pyrrole sub-units, which can be readily identified and used in determining the structure of the parent porphyrin.

Here is just a brief introduction to this compound(616-43-3)Related Products of 616-43-3, more information about the compound(3-Methyl-1H-pyrrole) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Synthesis of furan amines and their catalytic conversion into five-membered nitrogenous heterocycles》. Authors are Shuikin, N. I.; Petrov, A. D.; Glukhovtsev, V. G.; Bel’skii, I. F.; Skobtsova, G. E..The article about the compound:3-Methyl-1H-pyrrolecas:616-43-3,SMILESS:CC1=CNC=C1).Product Details of 616-43-3. Through the article, more information about this compound (cas:616-43-3) is conveyed.

CH2:CHCHO added to sylvan in AcOH in the presence of hydroquinone at 40° gave after 2 hrs. 65% 2-methyl-5-(3-oxopropyl)furan, b4 58°, n20D 1.4762, d20 1.0360; with 50% H2SO4 as a catalyst, the yield was 43%. The latter catalyst with crotonaldehyde similarly gave 53% 2-methyl-5-(1-methyl-3-oxopropyl)furan, b3 67°, 1.4730, 1.0093, while mesityl oxide gave 75% 2-methyl-5-(1,1-dimethyl-3-oxobutyl)furan, b2 61°, 1.4700, 0.9747. These carbonyl derivatives were hydrogenated in MeOH saturated with NH3 over Raney Ni at 100-50 atm. and 80° and gave: 2-methyl-5-(3-aminopropyl)-furan, b6 82°, 1.4840, 0.9758; 2-methyl-5-(1-methyl-3-amino-propyl)furan, b7 85°, 1.4800, 0.9591; 2-methyl-5-(1,1-dimethyl-3-aminobutyl)furan, b4 75°, 1.4741, 0.9365. The latter was hydrogenated at 250° over 15% Pt-asbestos to 2,4,4-trimethyl-5-butylpyrrolidine, b5 39°, 1.4444, 0.8319. Raman spectra of the products were reported.

Here is just a brief introduction to this compound(616-43-3)Product Details of 616-43-3, more information about the compound(3-Methyl-1H-pyrrole) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Category: chiral-oxygen-ligands. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 3-Methyl-1H-pyrrole, is researched, Molecular C5H7N, CAS is 616-43-3, about Comparison between CP/MAS 13C-NMR and pyrolysis-GC/MS in the structural characterization of humins and humic acids of soil and sediments. Author is Fabbri, D.; Mongardi, M.; Montanari, L.; Galletti, G. C.; Chiavari, G.; Scotti, R..

The chem. structure of humins (HUs) and humic acids (HAs) of terrestrial and marine environments was investigated by cross-polarization magic angle spinning 13C-NMR spectroscopy and pyrolysis-gas chromatog./mass spectrometry. Samples of HUs and HAs were obtained from sediments of the Adriatic Sea, the Lagoon of Ravenna (Adriatic Sea), and the Bubano Lake as well as from an agricultural soil. HUs showed pyrograms and NMR spectra different from those of related HAs. According to NMR spectra HUs were more aliphatic and contained fewer carboxyl groups than HAs, while pyrolyzates of HUs were characterized by higher levels of products arising from carbohydrates and lower levels of lignin methoxyphenols with respect to HAs. The relative content of paraffinic carbons determined by NMR was in good agreement with the relative abundance of unbranched aliphatic hydrocarbons released by pyrolysis. Both techniques evidenced the importance of polymethylene structures in HUs.

Here is just a brief introduction to this compound(616-43-3)Category: chiral-oxygen-ligands, more information about the compound(3-Methyl-1H-pyrrole) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Category: chiral-oxygen-ligands. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 3-Methyl-1H-pyrrole, is researched, Molecular C5H7N, CAS is 616-43-3, about Photosensitized oxygenation of 3-methylpyrrole involving a dioxetane intermediate. Author is Lightner, David A.; Low, Lawrence K..

The Rose Bengal-sensitized photooxidation of 3-methylpyrrole in MeOH gave 3% 3-methyl-3-methoxy-4-pyrrolin-2-one and 6% 3-hydroxy-3-methyl-4-pyrrolin-2-one via a dioxetane intermediate, 22% 3-methyl-5-methoxy-3-pyrrolin-2-one, 7% 4-methyl-5-methoxy-3-pyrrolin-2-one, 10% 5-hydroxy-3-methyl-3-pyrrolin-2-one, and 13% citraconimide.

Here is just a brief introduction to this compound(616-43-3)Category: chiral-oxygen-ligands, more information about the compound(3-Methyl-1H-pyrrole) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Application of 616-43-3. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 3-Methyl-1H-pyrrole, is researched, Molecular C5H7N, CAS is 616-43-3, about Structural studies on soil nitrogen by Curie-point pyrolysis Gas chromatography/mass spectrometry with nitrogen-selective detection. Author is Schulten, H.-R.; Sorge, C.; Schnitzer, M..

Curie-point pyrolysis-gas chromatog./mass spectrometry with N-selective detection was used to characterize the structure of organic N compounds in four mineral soils. The technique was found suitable for the fast, sensitive, and highly specific identification of N-containing pyrolysis products from whole soils with total N contents between 0.08 and 0.46%. In order to optimize the methodol., one agricultural soil was pyrolyzed at final temperatures of 573, 773, and 973 K. Almost no chem. alterations to identifiable pyrolysis products were observed when the final pyrolysis temperature was increased from 573 to 973 K. More than 50 N-containing pyrolysis products were identified, and were divided into compound classes characterized by specific mol. chem. structures. These included pyrroles, imidazoles, pyrazoles, pyridines, pyrimidines, pyrazines, indoles, quinolines, N derivatives of benzene, alkyl nitriles, and aliphatic amines. Three addnl. soil samples different in origin and N content were analyzed at 773 K and each showed a specific thermosensitive N-selective chromatogram. Many N-containing pyrolysis products were identified in all samples, which indicated general qual. regularities in the thermal release of N-containing pyrolysis products from the four soils. In the pyrolyzates of the investigated soils a number of compounds were identified, which is usually not detectable in pyrolysis-gas chromatog. spectrometry analyses with N-selective detection of plants and microorganisms. Among these were N derivatives of benzene and long-chain alkyl nitriles, which appear to be soil-specific and suggest significant transformations of organic N in soils. Thus, the results contribute to a better understanding of the mol.-chem. structure of unknown N.

Here is just a brief introduction to this compound(616-43-3)Application of 616-43-3, more information about the compound(3-Methyl-1H-pyrrole) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Bulky 2,6-diphenylphenylsulfanyl substituents efficiently inhibit aggregation in phthalocyanines and tetrapyrazinoporphyrazines and control their photophysical and electrochemical properties, published in 2017-01-31, which mentions a compound: 56413-95-7, mainly applied to magnesium zinc sulfanyl phthalocyanine tetrapyrazinoporphyrazine complex preparation redox potential; fluorescence magnesium zinc sulfanyl phthalocyanine tetrapyrazinoporphyrazine complex, COA of Formula: C6Cl2N4.

Octasubstituted zinc, metal-free and magnesium complexes of phthalocyanine and tetrapyrazinoporphyrazine bearing very bulky 2,6-diphenylphenylsulfanyl substituents were synthesized. The substituents efficiently inhibited aggregation of the dyes and only monomers were detected even at a concentration of 200 μM solution in toluene. Photophys. data indicated influence of the heavy-atom effect – magnesium complexes were more fluorescent (ΦF 0.40-0.51) and zinc complexes produced stronger the singlet oxygen (ΦΔ 0.56-0.72) in both series of compounds The presence of addnl. nitrogens in tetrapyrazinoporphyrazine core made it substantially more electron deficient when compared with corresponding phthalocyanine analogs. 2,6-Diphenylphenylsulfanyl substituents also increased electron deficient character of the core and influenced the photophys. properties.

Here is just a brief introduction to this compound(56413-95-7)COA of Formula: C6Cl2N4, more information about the compound(5,6-Dichloropyrazine-2,3-dicarbonitrile) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

COA of Formula: C6Cl2N4. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 5,6-Dichloropyrazine-2,3-dicarbonitrile, is researched, Molecular C6Cl2N4, CAS is 56413-95-7, about Electron-deficient acene-based liquid crystals: dialkoxydicyanopyrazinoquinoxalines. Author is Takeda, Takashi; Tsutsumi, Jun’ya; Hasegawa, Tatsuo; Noro, Shin-ichiro; Nakamura, Takayoshi; Akutagawa, Tomoyuki.

Three electron-accepting dialkoxydicyanopyrazinoquinoxaline derivatives showed properties of smectic (Sm) liquid crystals. Temperature-dependent X-ray diffraction studies were consistent with the formation of a bilayer structure through the π-overlap and interdigitation of alkoxy chains in the Sm liquid crystalline state. Intermol. dipole-dipole interactions between the cyano groups played an important role in stabilizing the bilayer structure and liquid crystalline properties. Elongation of the alkoxy chains from C6H13O- and/or C12H25O- to C18H37O- changed the mol. arrangement and the liquid crystal phase from SmA to SmC, suggesting the importance of the van-der-Waals interaction of CnH2n+1O- chains for stabilizing the liquid crystalline phase. A hole-mobility value of 5 × 10-3 cm2 V-1 s-1 was observed for the SmA phase of bis(dodecyloxy)pyrazino[2,3-b]quinoxaline-2,3-dicarbonitrile at 438 K based on transient photocurrent measurements. The synthesis of the target compounds was achieved by a reaction of 5,6-dichloro-2,3-pyrazinedicarbonitrile with 4,5-bis(hexyloxy)-1,2-benzenediamine, 4,5-bis(dodecyloxy)-1,2-benzenediamine, 4,5-bis(octadecyloxy)-1,2-benzenediamine. The title compounds thus formed included bis(alkoxy)pyrazino[2,3-b]quinoxaline-2,3-dicarbonitrile derivatives (electron-deficient acene derivatives, heterocyclic anthracene analogs).

Here is just a brief introduction to this compound(56413-95-7)COA of Formula: C6Cl2N4, more information about the compound(5,6-Dichloropyrazine-2,3-dicarbonitrile) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 56413-95-7, is researched, SMILESS is N#CC1=NC(Cl)=C(Cl)N=C1C#N, Molecular C6Cl2N4Journal, Coloration Technology called Synthesis and solution studies on azaphthalocyanines with quaternary aminoethyl substituents, Author is Kobak, Rabia Z. Uslu; Gul, Ahmet, the main research direction is magnesium cobalt zinc substituted azaphthalocyanine preparation UV.Synthetic Route of C6Cl2N4.

A pyrazinedinitrile derivative carrying dimethylaminoethylsulfanyl groups at positions 5 and 6 was synthesized from 2-dimethylaminoethanethiol hydrochloride and 2,3-dicarbonitrile-5,6-dichloropyrazine. The dicarbonitrile gave magnesium azaphthalocyanine (MgAzaPc) when reacted with magnesium propoxide in propanol. The conversion of the MgAzaPc to a metal-free derivative was achieved by treatment with trifluoroacetic acid. Incorporation of transition metal ions into the inner core of azaphthalocyanine was accomplished by treatment of the metal-free derivative with metal acetates, i.e. Zn(OAc)2, Co(OAc)2. These azaphthalocyanines were converted into water-soluble quaternised products by reaction with Me iodide. Aggregation phenomena were followed for magnesium azaphthalocyanine with quaternisable dimethylamino substituents within a specific range of pH. The compounds were characterized by FTIR, 1H NMR, mass and UV-visible spectral data.

Here is just a brief introduction to this compound(56413-95-7)Synthetic Route of C6Cl2N4, more information about the compound(5,6-Dichloropyrazine-2,3-dicarbonitrile) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Reference of cis-4-Aminocyclohexane carboxylic acid. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Pd-Catalyzed γ-C(sp3)-H Fluorination of Free Amines. Author is Chen, Yan-Qiao; Singh, Sukriti; Wu, Yongwei; Wang, Zhen; Hao, Wei; Verma, Pritha; Qiao, Jennifer X.; Sunoj, Raghavan B.; Yu, Jin-Quan.

The first example of free amine γ-C(sp3)-H fluorination is realized using 2-hydroxynicotinaldehyde as the transient directing group. A wide range of cyclohexyl and linear aliphatic amines could be fluorinated selectively at the γ-Me and methylene positions. Electron withdrawing 3,5-disubstituted pyridone ligands were identified to facilitate this reaction. Computational studies suggest that the turnover determining step is likely the oxidative addition step for methylene fluorination, while it is likely the C-H activation step for Me fluorination. The explicit participation of Ag results in a lower energetic span for methylene fluorination and a higher energetic span for Me fluorination, which is consistent with the exptl. observation that the addition of silver salt is desirable for methylene but not for Me fluorination. Kinetic studies on Me fluorination suggest that the substrate and PdL are involved in the rate-determining step, indicating that the C-H activation step may be partially rate-determining Importantly, an energetically preferred pathway has identified an interesting pyridone-assisted bimetallic transition state for the oxidative addition step in methylene fluorination, thus uncovering a potential new role of the pyridone ligand.

Here is just a brief introduction to this compound(3685-23-2)Reference of cis-4-Aminocyclohexane carboxylic acid, more information about the compound(cis-4-Aminocyclohexane carboxylic acid) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate