This type of reactivity has quickly become one of the cornerstones of modern catalysis .In a patent, Computed Properties of C17H14O, name is 1,5-Diphenylpenta-1,4-dien-3-one, belongs to chiral-oxygen-ligands compound, introducing its new discovery. Computed Properties of C17H14O
A set of bench-stable ruthenium complexes with new N,N,N-tridentate coordinating pincer-type pyridyl-bis(pyridylideneamide) ligands was synthesized in excellent yields, with the pyridylidene amide in meta or in para position (m-PYA and p-PYA, respectively). While complex [Ru(p-PYA)(MeCN)3]2+ is catalytically silent in transfer hydrogenation, its meta isomer [Ru(m-PYA)(MeCN)3]2+ shows considerable activity with turnover frequencies at 50% conversion TOF50 = 100 h-1. Spectroscopic, electrochemical, and crystallographic analyses suggest considerably stronger donor properties of the zwitterionic m-PYA ligand compared to the partially pi-acidic p-PYA analogue, imparted by valence isomerization. Further catalyst optimization was achieved by exchanging the ancillary MeCN ligands with imines (4-picoline), amines (ethylenediamine), and phosphines (PPh3, dppm, dppe). The most active catalyst was comprised of the m-PYA pincer ligand and PPh3, complex [Ru(m-PYA)(PPh3)(MeCN)2]2+, which reached a TOF50 of 430 h-1 under aerobic conditions and up to 4000 h-1 in the absence of oxygen. The presence of oxygen reversibly deactivates the catalytically active species, which compromises activity, but not longevity of the catalyst. Ligand exchange kinetic studies by NMR spectroscopy indicate that the strong trans effect of the phosphine is critical for high catalyst activity. Diaryl, aryl-alkyl, and dialkyl ketones were hydrogenated with high conversion, and alpha,beta-unsaturated ketones produced selectively the saturated ketone as the only product due to exclusive C=C bond hydrogenation, a distinctly different selectivity from most other transfer hydrogenation catalysts.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about538-58-9 . Computed Properties of C17H14O
Reference：
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate