Category: 3685-23-2

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 3685-23-2, is researched, Molecular C7H13NO2, about Cytotoxic T lymphocyte epitope analogues containing cis- or trans-4-aminocyclohexanecarboxylic acid residues, the main research direction is cytotoxic T lymphocyte aminocyclohexanecarboxylic acid analog immunotherapy HLA antigen; structure activity aminocyclohexanecarboxylic acid analog cytotoxic T lymphocyte.SDS of cas: 3685-23-2.

In order to improve the immunotherapeutical potential of H-Cys-Leu-Gly-Gly-Leu-Leu-Thr-Met-Val-OH (CLG) peptide, an Epstein-Barr virus (EBV) subdominant epitope derived from the membrane protein LMP2, we have synthesized and tested CLG analogs containing cis- and/or trans-4-aminocyclohexanecarboxylic acid (ACCA) replacing Gly-Gly and/or Thr-Met dipeptide units. All pseudopeptides were tested for metabolic stability and for their capacity to bind HLA-A2 mols. and to sensitize target cells to lysis. All new compounds exhibited higher enzymic resistance compared to the original CLG and some trans-ACCA-derivatives were able to associate HLA-A2 and to efficiently stimulate CTL responses directed against the CLG natural epitope.

Compounds in my other articles are similar to this one(cis-4-Aminocyclohexane carboxylic acid)SDS of cas: 3685-23-2, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 3685-23-2, is researched, Molecular C7H13NO2, about Analysis of metabolites and metabolic mechanism in Bt transgenic and non-transgenic maize, the main research direction is metabolite metabolic mechanism Bt transgenic maize.Name: cis-4-Aminocyclohexane carboxylic acid.

The gas chromatog.-mass spectrometry was used to isolate and identify metabolites of non-transgenic and Bacillus thuringiensis transgenic maize. The non-targeted metabolomics technique was used to anal. the metabolic pathway and mechanism of two kinds of maize. The methanol was used as extractant and the N,O-bis(trimethylsilyl) trifluoroacetamide was used as derivatization reagent. 38 kinds of metabolites were isolated and identified from non-transgenic maize, and 61 kinds of metabolites were isolated and identified in Bacillus thuringiensis transgenic maize. The specific metabolites between non-transgenic and Bacillus thuringiensis transgenic maize were analyzed. The metabolic pathway of specific metabolites was analyzed by KEGG annotation. The metabolic mechanism of non-transgenic maize and Bacillus thuringiensis transgenic maize was explored. The result indicated there were more metabolites involved in metabolic pathways in Bacillus thuringiensis transgenic maize than in non-transgenic maize, and tricarboxylic acid cycle and energy metabolism pathways of Bacillus thuringiensis transgenic maize are found to be higher than that of non-transgenic maize. The metabolic pathway of Bacillus thuringiensis transgenic maize conforms to the biol. activity law.

Although many compounds look similar to this compound(3685-23-2)Name: cis-4-Aminocyclohexane carboxylic acid, numerous studies have shown that this compound(SMILES:N[C@H]1CC[C@H](CC1)C(O)=O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Application of 3685-23-2. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Synthesis and properties of 2-azabicyclo[2:2:2]octan-3-one and 6-azabicyclo[3:2:1]octan-7-one.

Optimal reaction conditions for the synthesis of lactams of cis-3- and -4-ACH acids and their derivatives were determined 1H NMR spectral data confirmed different configuration of lactams of cis-3- and cis-4-derivatives Possibility to apply lactams for the separation of cis- and trans-isomers was investigated.

Although many compounds look similar to this compound(3685-23-2)Application of 3685-23-2, numerous studies have shown that this compound(SMILES:N[C@H]1CC[C@H](CC1)C(O)=O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Biancalana, Lorenzo; Bresciani, Giulio; Marchetti, Fabio; Pampaloni, Guido published an article about the compound: cis-4-Aminocyclohexane carboxylic acid( cas:3685-23-2,SMILESS:N[C@H]1CC[C@H](CC1)C(O)=O ).SDS of cas: 3685-23-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:3685-23-2) through the article.

The serendipitous discovery of the unprecedented route to a zwitterionic imidazolium mol. with the two nitrogen atoms substituted with 4-cyclohexanecarboxylic acid was reported. To build the five-membered ring, glyoxal played the double role of source for C2 and unusually C1 units, the latter via thermal decomposition afforded carbon monoxide as side-product. The product was characterized by elemental anal., multinuclear NMR, IR and ESI-MS spectroscopy.

Although many compounds look similar to this compound(3685-23-2)SDS of cas: 3685-23-2, numerous studies have shown that this compound(SMILES:N[C@H]1CC[C@H](CC1)C(O)=O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Preparation and properties of ruthenium catalysts of the liquid-phase hydrogenation of aromatic compounds.Recommanded Product: 3685-23-2.

The activity and sp. surface of 5% Ru catalysts increased in the order of supports SiO2 < γ-Al2O3 < C, but the specific activity per m2 surface was independent of the support or the method of catalyst preparation A catalyst prepared by treating C with Ru(OH)Cl3 at pH 5.9-6.1 followed by reduction with H at 300° or NaBH4 at 20° had the highest dispersion and specific activity by weight of those studied in the hydrogenation of p-H2NC6H4CO2- NH4+ (p-I). Hexahydroarom. acids were formed in 86-98% yield from m- and p-I, p-H2NCH2C6H4CO2- NH4+, p-Me3CC6H4CO2Na, ammonium isonicotinate and BzOH, and acenaphthene gave >90% perhydroacenaphthene at 80-145° and 60-80 atm.

Compounds in my other articles are similar to this one(cis-4-Aminocyclohexane carboxylic acid)Recommanded Product: 3685-23-2, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 3685-23-2, is researched, SMILESS is N[C@H]1CC[C@H](CC1)C(O)=O, Molecular C7H13NO2Journal, Article, Bioorganic & Medicinal Chemistry called Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT), Author is Ding, Yun; Belyanskaya, Svetlana; DeLorey, Jennifer L.; Messer, Jeffrey A.; Joseph Franklin, G.; Centrella, Paolo A.; Morgan, Barry A.; Clark, Matthew A.; Skinner, Steven R.; Dodson, Jason W.; Li, Peng; Marino, Joseph P. Jr.; Israel, David I., the main research direction is soluble epoxide hydrolase inhibitor GSK2256294 DNA encoded library; DNA-encoded library technology; Soluble epoxide hydrolase.COA of Formula: C7H13NO2.

Inhibition of soluble epoxide hydrolase (sEH) has recently emerged as a new approach to treat cardiovascular disease and respiratory disease. Inhibitors based on 1,3,5-triazine chemotype were discovered through affinity selection against two triazine-based DNA-encoded libraries. The structure and activity relationship study led to the expansion of the original 1,4-cycloalkyl series to related aniline, piperidine, quinoline, aryl-ether and benzylic series. The 1,3-cycloalkyl chemotype led to the discovery of a clin. candidate (GSK2256294, I) for COPD.

Compounds in my other articles are similar to this one(cis-4-Aminocyclohexane carboxylic acid)COA of Formula: C7H13NO2, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Recommanded Product: cis-4-Aminocyclohexane carboxylic acid. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Pd-Catalyzed γ-C(sp3)-H Fluorination of Free Amines. Author is Chen, Yan-Qiao; Singh, Sukriti; Wu, Yongwei; Wang, Zhen; Hao, Wei; Verma, Pritha; Qiao, Jennifer X.; Sunoj, Raghavan B.; Yu, Jin-Quan.

The first example of free amine γ-C(sp3)-H fluorination is realized using 2-hydroxynicotinaldehyde as the transient directing group. A wide range of cyclohexyl and linear aliphatic amines could be fluorinated selectively at the γ-Me and methylene positions. Electron withdrawing 3,5-disubstituted pyridone ligands were identified to facilitate this reaction. Computational studies suggest that the turnover determining step is likely the oxidative addition step for methylene fluorination, while it is likely the C-H activation step for Me fluorination. The explicit participation of Ag results in a lower energetic span for methylene fluorination and a higher energetic span for Me fluorination, which is consistent with the exptl. observation that the addition of silver salt is desirable for methylene but not for Me fluorination. Kinetic studies on Me fluorination suggest that the substrate and PdL are involved in the rate-determining step, indicating that the C-H activation step may be partially rate-determining Importantly, an energetically preferred pathway has identified an interesting pyridone-assisted bimetallic transition state for the oxidative addition step in methylene fluorination, thus uncovering a potential new role of the pyridone ligand.

Compounds in my other articles are similar to this one(cis-4-Aminocyclohexane carboxylic acid)Recommanded Product: cis-4-Aminocyclohexane carboxylic acid, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Category: chiral-oxygen-ligands. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about The uptake and radioautographical localization of (±)-[3H]cis-aminocyclohexanecarboxylic acid by the isolated frog retina. Author is Cunningham, Jo; Marshall, J.; Neal, M. J..

Uptake of aminocyclohexanecarboxylic acid (I) [39275-59-7] by frog retinas was temperature-sensitive and highly Na-dependent, and was inhibited by GABA [56-12-2], L-2,4-diaminobutyric acid (II) [1758-80-1], and β-alanine [107-95-9] with IC50 values of 0.32, 0.23, and 9.0 mM, resp. Radioautog. studies indicated that the sites of I-3H and GABA-3H uptake were identical, the compounds being accumulated almost exclusively in the horizontal cells. II-3H and β-alanine-3H were accumulated predominantly in the Mueller cells and photoreceptors, resp. Although II possesses affinity for the I (GABA) transport system in the horizontal cells, I and GABA apparently have no affinity for the (high affinity) II transport system in the Mueller cells.

In some applications, this compound(3685-23-2)Category: chiral-oxygen-ligands is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Related Products of 3685-23-2. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Proton NMR spectroscopic study of the stereoconfiguration and conformation of cis and trans isomers of 3- and 4-aminocyclohexylalkanoic acids. Author is Palaima, A.; Staniulyte, Z.; Juodvirsis, A..

1H NMR spectral data for cyclohexane H1, H3 or H1, H4 protons of cis- and trans-3- and 4-aminocyclohexanealkanoic acids were successfully used for determination of the stereoconfigurations and conformational equilibrium of sep. isomers and for determination of cis/trans ratio in their mixtures by using Pr(NO3)3 and Eu(fod)3 as shift-reagents. For that purpose NMR data of the alkanoic substituents of the cyclohexane ring can also be used.

In some applications, this compound(3685-23-2)Related Products of 3685-23-2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

HPLC of Formula: 3685-23-2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Investigating the Stability of Double Head to Tail Dimers and Ribbons in Multicomponent Crystals of cis-4-Aminocyclohexanecarboxylic Acid with Water and Oxalic Acid. Author is Mora, Asiloe J.; Belandria, Lusbely M.; Avila, Edward E.; Seijas, Luis E.; Delgado, Gerzon E.; Miro, Aira; Almeida, Rafael; Brunelli, Michela; Fitch, Andrew N..

The current contribution aims to study the stability of commonly occurring motifs present in certain amino acid structures after introducing addnl. mols. to form multicomponent crystals. The crystal structures of the amino acid cis-4-aminocyclohexanecarboxylic acid hemihydrate I and dehydrate II forms and that of its oxalate salt cocrystd. with oxalic acid III, were studied employing a combination of techniques. Both single-crystal and powder x-ray diffraction were used to solve the structures, while temperature-control powder X-ray diffraction was used to follow the dehydration of I. Regardless of the added mols. that induce modifications of the intermol. interactions within the crystals, some recurring supramol. structures were identified: double head to tail dimers, graph symbol R22(16), and ribbons, graph symbol R22(16)R34(10). Stabilities of these supramol. motifs were studied using theor. modeling with DFT/B3LYP/6-31++G (d,p) and PM6-D2H calculations The theor. calculations reproduced the exptl. findings, confirming the extraordinary stability of these motifs. The mol. recognition of amino acid pairs to form double head to tail-dimers is undoubtedly the initial driving force for the crystal formation in all the three crystals studied.

In some applications, this compound(3685-23-2)HPLC of Formula: 3685-23-2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate