Category: chiral-oxygen-ligands

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: cis-4-Aminocyclohexane carboxylic acid(SMILESS: N[C@H]1CC[C@H](CC1)C(O)=O,cas:3685-23-2) is researched.Category: chiral-oxygen-ligands. The article 《Characterization of an inhibitory receptor in rat hippocampus. A microiontophoretic study using conformationally restricted amino acid analogs》 in relation to this compound, is published in British Journal of Pharmacology. Let’s take a look at the latest research on this compound (cas:3685-23-2).

The inhibitory potencies of GABA [56-12-2], β-alanine [107-95-9], and glycine [56-40-6] in rat hippocampal pyramidal cells were determined and compared with those of substituted aminocyclopentane and aminocyclohexane carboxylic acids (ACPC and ACHC resp.). The order of effectiveness of the small aliphatic amino acids was GABA > β-alanine > glycine. GABA-induced inhibition was inhibited by iontophoresis of bicuculline or picrotoxin but not strychnine-HCl. The inhibitory abilities of the substituted ACPC and ACHC derivatives was a direct function of the separation of NH2 and CO2H groups in both series of cyclic amino acids. The most potent inhibition was observed when the spatial separation was similar to that of the extended GABA mol. (4.74 Å). Inhibition by (±)-cis-3-aminocyclopentanecarboxylic acid was blocked by simultaneous application of bicuculline or picrotoxin, but not by strychnine-HCl. The physiol. active conformation of GABA is probably the fully extended mol. and one dimension of the postsynaptic receptor site is probably within the range 4.2-4.8 Å.

Compound(3685-23-2)Recommanded Product: 3685-23-2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(cis-4-Aminocyclohexane carboxylic acid), if you are interested, you can check out my other related articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 616-43-3, is researched, SMILESS is CC1=CNC=C1, Molecular C5H7NJournal, Zeitschrift fuer Lebensmittel-Untersuchung und -Forschung called Model reactions on roast aroma formation. III. Mass spectrometric identification of pyrroles from the reaction of serine and threonine with sucrose under the conditions of coffee roasting, Author is Baltes, Werner; Bochmann, Gloria, the main research direction is pyrrole aroma coffee roasting model; serine threonine sucrose pyrrole.Formula: C5H7N.

Numerous alkyl- and acylpyrroles, two 2,3-dihydro[1H]pyrrolizines, furfurylpyrroles, and 1 furanylpyrrole were identified in the volatiles of roasting serine, threonine, and sucrose. The formation of the alkylpyrroles was suggested to proceed via a pyrolytic pathway because they were formed in the absence of sucrose. The retention indexes and mass spectra are reported together with selected mass spectrometric fragmentations. A large number of the identified compounds were also recognized in roast coffee volatiles.

Compound(616-43-3)Formula: C5H7N received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(3-Methyl-1H-pyrrole), if you are interested, you can check out my other related articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Bioresource Technology called Pyrolysis of fast-growing aquatic biomass -Lemna minor (duckweed): Characterization of pyrolysis products, Author is Muradov, Nazim; Fidalgo, Beatriz; Gujar, Amit C.; T-Raissi, Ali, which mentions a compound: 616-43-3, SMILESS is CC1=CNC=C1, Molecular C5H7N, Recommanded Product: 616-43-3.

The aim of this work was to conduct the exptl. study of pyrolysis of fast-growing aquatic biomass -Lemna minor (commonly known as duckweed) with the emphasis on the characterization of main products of pyrolysis. The yields of pyrolysis gas, pyrolytic oil (bio-oil) and char were determined as a function of pyrolysis temperature and the sweep gas (Ar) flow rate. Thermogravimetric/differential thermogravimetric (TG/DTG) analyses of duckweed samples in inert (helium gas) and oxidative (air) atm. revealed differences in the TG/DTG patterns obtained for duckweed and typical plant biomass. The bio-oil samples produced by duckweed pyrolysis at different reaction conditions were analyzed using GC-MS technique. It was found that pyrolysis temperature had minor effect on the bio-oil product slate, but exerted major influence on the relative quantities of the individual pyrolysis products obtained. While, the residence time of the pyrolysis vapors had negligible effect on the yield and composition of the duckweed pyrolysis products.

Compound(616-43-3)Recommanded Product: 616-43-3 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(3-Methyl-1H-pyrrole), if you are interested, you can check out my other related articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《The polarographic reducibility of some alkylpyrroles》. Authors are Scaramelli, Giuseppe.The article about the compound:3-Methyl-1H-pyrrolecas:616-43-3,SMILESS:CC1=CNC=C1).Related Products of 616-43-3. Through the article, more information about this compound (cas:616-43-3) is conveyed.

In addition to pyrrole itself, the following derivatives were found to be polarographically nonreducible: 1- and 2-Me, 1-allyl, 2,4-di-Me and 2,5-di-Me, 3-methyl-4-ethyl, 2,3,5-trimethyl, 2,5-dimethyl-1-ethyl, 2,4-dimethyl-3-ethyl, 2,4-dimethyl-3-propyl, 2,4-dimethyl-3-ethyl-1-carbethoxy, and 2,4-dimethyl-3,5-dicarbethoxy.

Here is just a brief introduction to this compound(616-43-3)Related Products of 616-43-3, more information about the compound(3-Methyl-1H-pyrrole) is in the article, you can click the link below.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 5,6-Dichloropyrazine-2,3-dicarbonitrile(SMILESS: N#CC1=NC(Cl)=C(Cl)N=C1C#N,cas:56413-95-7) is researched.Application In Synthesis of 2-(Furan-2-yl)-2-oxoacetaldehyde. The article 《Solid-Phase Synthesis of Aza-phthalocyanine-Oligonucleotide Conjugates and Their Evaluation As New Dark Quenchers of Fluorescence》 in relation to this compound, is published in Bioconjugate Chemistry. Let’s take a look at the latest research on this compound (cas:56413-95-7).

Hydrophobic non-aggregating metal-free azaphthalocyanines (AzaPc) of the tetrapyrazinoporphyrazine type were synthesized, characterized, and used for oligonucleotide labeling. Both 3′-end and 5′-end labeling methods using solid phase synthesis suitable for automatic processes in the DNA/RNA synthesizer were developed. The hydrophobic character of AzaPc enabled the anchoring of the conjugates on reverse phase of the oligonucleotide purification cartridge, thus enabling their simple purification AzaPc did not show any fluorescence and extremely low singlet oxygen quantum yields (ΦΔ = 0.015-0.018 in DMF) in a monomeric state due to ultrafast intramol. charge transfer. That is why they were investigated as a new dark quencher structural type. They profit particularly from absorption in a wide range of wavelengths (300-740 nm) that covers all fluorophores used in hybridization assays nowadays. As an example, quenching efficiency was evaluated in a simple hybridization assay using monolabeled probes. AzaPc-based probes efficiently quenched both fluorescein and Cy5 fluorescence by both resonance energy transfer and contact quenching. The results were compared with three established dark quenchers, and the AzaPc exerted better (BHQ-1 and BHQ-2) or comparable (BBQ-650) quenching efficiencies for both fluorophores.

From this literature《Solid-Phase Synthesis of Aza-phthalocyanine-Oligonucleotide Conjugates and Their Evaluation As New Dark Quenchers of Fluorescence》,we know some information about this compound(56413-95-7)Product Details of 56413-95-7, but this is not all information, there are many literatures related to this compound(56413-95-7).

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Practical synthesis of thieno[3,2-b]pyrrole》. Authors are Matteson, Donald S.; Snyder, H. S..The article about the compound:3-Methyl-1H-pyrrolecas:616-43-3,SMILESS:CC1=CNC=C1).Application of 616-43-3. Through the article, more information about this compound (cas:616-43-3) is conveyed.

cf. C.A. 51, 16422a. KCNS(200 g.) in 250 ml. MeOH at -75° (Dry Ice-Me2CO bath) stirred with dropwise addition of 159.6 g. Br in 125 ml. MeOH at -75° and the mixture kept below -60°, the thiocyanogen solution cooled to -75° and treated rapidly with 67.1 g. redistilled pyrrole in 250 ml. MeOH at -75° and the mixture stirred (with cooling bath removed) until the temperature rose to -25°, poured onto 2 kg. crushed ice and stirred with 300 g. NaCl, filtered through a 5-6-in. Buchner funnel and the ice and solids washed freely with H2O, the crude 3-thiocyanopyrrole (I) dried in vacuo and clarified in 100 ml. CH2Cl2 and 500 ml. methylcyclohexane (MgSO4 and Darco) at 40°, the colorless solution chilled and seeded, kept 17 hrs. at 0°, and chilled to -20° gave 62 g. I, m. 40-4°, infrared spectrum identical with that of I prepared from Cu(CNS)2 and pyrrole. I stains the skin deep red and may cause burning or itching sensations. The use of rubber gloves is mandatory and contacted areas should be washed immediately with soap and H2O and treated with 3% H2O2. Pyrrole (0.71 g.) in 75 ml. MeOH stirred at 0-5° (N atm.) with portionwise addition of 0.2 mole Cu(CNS)2 [on basis of (NCS)2 analysis] in a few min. and stirring continued 50 min. at 0-5°, the mixture filtered and the CuCNS washed with 50 ml. MeOH, the filtrate and washings poured onto 300 g. crushed ice and 100 g. NaCl added, the mixture filtered and the solids extracted with 225 ml. methylcyclohexane, the solution treated with Darco and cooled, seeded, and kept 17 hrs. at 0° gave 5.83 g. I, m. 41.5-43° (methylcyclohexane). As a route to 3-(alkylthio)pyrroles, attempts to isolate 3-mercaptopyrrole (II), 3-RSC4H4N (R = H) (IIa), were made but abandoned when a more promising way was found. Mg (1.87 g.) in 125 ml. MeOH (N atm.) at -20° kept 1 hr. with 6.2 g. I and the mixture poured into 500 ml. H2O, 200 ml. Et2O, and sufficient solid CO2 to dissolve the precipitated Mg(OH)2, the aqueous phase extracted with Et2O and the dried Et2O solutions evaporated in vacuo, the residue sublimed at 75°/0.1 mm. and the product (6.8 g.) recrystallized from PhMe, resublimed, recrystallized from dilute MeOH, and resublimed at 55-65°/0.1 mm. gave S-3-pyrrolyl O-Me thioimidocarbonate, II [R = C(:NH)OMe], m. 77-80°. I(6.21 g.) and 8.5 g. MeI in 50 ml. MeOH at -20° (N atm.) stirred with dropwise addition in 10 min. of 7.9 g. 85% KOH in 20 ml. H2O and 20 ml. MeOH and stirring continued 1.5 hrs. without cooling, the excess alkali neutralized with solid CO2 and the mixture poured into 500 ml. H2O containing 100 g. NaCl, the mixture extracted 3 times with 50 ml. CH2Cl2 and the dried solution (K2CO3) evaporated in vacuo, the residue distilled, and the product (5.1 g.) redistilled gave II (R = Me) (IIb), b12-13 88-9°. The excellent (90%) yield of IIb showed that the extremely unstable anion of IIa exists long enough to displace halide ions from a moderately active alkyl halide. I (62.1 g.) and 83.5 g. BrCH2CO2H in 500 ml. MeOH at -50° stirred rapidly with addition of 123 g. 85% KOH in 500 ml. 50% dilute MeOH in 10 min. and stirring continued 2 hrs. without cooling, the mixture brought to pH 8 with solid CO2 and the solvent evaporated in vacuo (warm H2O bath to avoid bumping), the solid residue taken up in 500 ml. CH2Cl2 and the mixture stirred with controlled addition of 375 ml. ice-cold 4N HCl, the aqueous phase extracted twice with 250 ml. CH2Cl2 and the combined dried CH2Cl2 solutions treated with Darco and filtered, the filtrate saturated with excess dry NH3, and filtered gave 78 g. II (R = CH2CO2NH4) (IIc), m. 127-33°, purified by treatment of IIc with N HCl and extraction with CH2Cl2, dehydration over MgSO4, and crystallization by treatment with anhydrous NH3 to give IIc, m. 125-33°; Ca salt-2H2O, m. 112-20° (decomposition). IIc in MeOH refluxed 20 hrs. with ZnCl2 and the product purified by extraction followed by distillation in a sublimation apparatus at 80°/0.1 mm. gave the liquid ester II (R = CH2CO2Me). BrCH2CH(OEt)2 failed to react with I under the above conditions and active alkyl halides such as PhCOCH2Br, BrCH2CO2Et, and ClCH2COCO2H appeared to be attacked by OH- more rapidly than was I and also failed to give sulfides. IIc (17.42 g.) and 250 ml. CH2Cl2 shaken with 30 ml. ice-cold 6N HCl and the aqueous phase extracted twice with 250 ml. CH2Cl2, the combined CH2Cl2 extracts dried (MgSO4) and treated with Darco, filtered and the filtrates combined with the 150 ml. CH2Cl2 washings of the Mg2SO4, the CH2Cl2 solution added dropwise in 50 min. to the most vigorously agitated region of 400 g. well-stirred polyphosphoric acid at 120-3° with free vaporization of the CH2Cl2, the mixture cooled below 100° and added slowly with stirring to 1200 ml. H2O and 750 ml. EtOAc, the stirring continued 30 min. and the aqueous layer extracted with 250 ml. EtOAc, the aqueous layer saturated with 300 g. NaCl and extracted twice with 250 ml. EtOAc, the emulsion layer neutralized with Na2CO3 and warmed on a steam bath prior to a 3-fold extraction with 100 ml. portions of EtOAc, the combined EtOAc solutions washed with aqueous NaHCO3 and dried over MgSO4, evaporated in vacuo, and the residue sublimed twice at 120°/0.1 mm. gave 5.0 g. product, m. 183-8.5°, purified by sublimation twice, recrystallization twice from aqueous HCONMe2 and sublimation twice, treatment with Darco, and recrystallization from MeOH to give 2H,3H-thieno[3,2-b]pyrrol-3-one (III), m. 187-90°, λ 330, 303 (min.), 279, 236 (min.) mμ (ε 7400, 3900, 16,000, 500, 95% alc.), ν 3140, 1635 cm.-1 (Nujol). III (0.28 g.) in 35 ml. 95% alc. refluxed 1 hr. with 2.5 g. Raney Ni (W6) and the solution filtered, the residue washed with alc. and the alc. solutions evaporated in vacuo, the residue sublimed, and the product (0.06 g.) recrystallized from H2O gave 23 mg. 2-acetylpyrrole, m. 89-91°, identical with that prepared from C4H4NMgBr and AcCl. III (1.39 g.) and 1.5 g. NaBH4 in 50 ml. MeOH refluxed 16 hrs. under N and the mixture poured into 200 ml. 15% aqueous NaCl, extracted 3 times with 50 ml. CH2Cl2 and the dried extract evaporated, the residue sublimed at 6070°/0.1 mm., and the 0.76 g. product recrystallized from Et2O-C5H12 at -70° and resublimed 3 times gave thieno[3,2-b]pyrrole, m. 25-8°, λ 260, 233 (min.) mμ (ε 11,800, 4900, 95% alc.), infrared spectrum and that of a less pure sample synthesized from thiophene (cf. Snyder, et al., C.A. 51, 13846b) given.

Compound(616-43-3)Application of 616-43-3 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(3-Methyl-1H-pyrrole), if you are interested, you can check out my other related articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Formula: C7H13NO2. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Synthesis of di- and tripeptides containing 4-aminocyclohexanecarboxylic acid. Author is Chen, Wen-Yih; Olsen, Richard K..

Amino acid derivatives were coupled to cis- and trans-4-aminocyclohexanecarboxylic acid with diethylphosphoryl cyanide as coupling reagent. Treatment of trans-I (R = Me3CO2C, R1 = OH) with diethylphosphoryl cyanide, followed by condensation with L-valine Me ester gave trans I (R = Me3CO2C, R1 = Val-OMe) (II). Deprotection and coupling of II with N-tert-butoxycarbonyl-L-alanine gave trans-I (R = Me3CO2C-Ala-, R1 = Val-OMe). Similar transformations were effected with cis-I (R = Me3CO2C, R1 = OH). Other coupling procedures investigated were the carbodiimide, p-nitrophenyl active ester, and sym. anhydride methods, which were less satisfactory for coupling to cyclohexane amino acids.

Compound(3685-23-2)Formula: C7H13NO2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(cis-4-Aminocyclohexane carboxylic acid), if you are interested, you can check out my other related articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Sicre, M. A.; Peulve, S.; Saliot, A.; de Leeuw, J. W.; Baas, M. researched the compound: 3-Methyl-1H-pyrrole( cas:616-43-3 ).COA of Formula: C5H7N.They published the article 《Molecular characterization of the organic fraction of suspended matter in the surface waters and bottom nepheloid layer of the Rhone Delta using analytical pyrolysis》 about this compound( cas:616-43-3 ) in Organic Geochemistry. Keywords: benthic nepheloid layer formation Rhone Delta; organic suspended matter Rhone Delta. We’ll tell you more about this compound (cas:616-43-3).

Curie Point-pyrolysis-gas chromatog. (CuPy-GC) and Curie Point-pyrolysis-gas chromatog.-mass spectrometry (CuPy-GC-MS) were applied to characterize the macromol. content of the suspended particles in the surface waters and benthic nepheloid layer of the Rhone Delta. The chromatogram of the pyrolyzate of the Rhone River particles revealed a low pyrolysis yield from the riverine material in which polysaccharides and lipid-derived substances prevailed. The absence of levoglucosan and other pyrolysis products related to cellulose suggested that no intact polysaccharides were present. Lignin-derived products were virtually absent. In the salinity gradient, a wide variety of products, including saturated and monounsaturated acids, phytadienes, n-alkylnitriles and pyrolysis products from proteins were determined, indicating a major contribution from freshly produced autochthonous material. A suite of dipeptides of bacterial origin was also identified. Lignin-derived products from terrigenous sources were minor. Further offshore qual. differences, with respect to the previous samples were apparent. Polysaccharides were less pronounced, possibly due to the dilution of the suspended load of the waters, and/or the microbial consumption of these readily degradable compounds In contrast, the relative abundances of autochthonously derived compounds increased as a result of nutrient inputs from the Rhone River which fertilize coastal waters. The occurrence of 1,1,3,3,5,5, hexamethylcyclotrioxane as well s styrene provided indications of anthropogenic inputs to the site. The macromol. constituents of suspended solids in the benthic nepheloid layer strikingly resembled those of the riverine material. Polysaccharides together with phytadienes and C14, C16 and C18 acids accounted for the major pyrolysis products. The persistence of this fingerprint in the benthic layer was observed from the mouth to stations ZD1 and ZA7. Beyond this point, due to the influence of the Liguro-Provencal current flowing westwards, the composition of the pyrolyzates changed towards a marine signature. Flocculation of suspended matter in which polysaccharides would make particles stick together or salt flocculation were proposed as an alternative scenario to explain the formation of the nepheloid layer.

Compound(616-43-3)COA of Formula: C5H7N received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(3-Methyl-1H-pyrrole), if you are interested, you can check out my other related articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Sinninghe Damste, Jaap S.; Eglinton, Timothy I.; de Leeuw, Jan W. researched the compound: 3-Methyl-1H-pyrrole( cas:616-43-3 ).Reference of 3-Methyl-1H-pyrrole.They published the article 《Alkylpyrroles in a kerogen pyrolysate: evidence for abundant tetrapyrrole pigments》 about this compound( cas:616-43-3 ) in Geochimica et Cosmochimica Acta. Keywords: sedimentary rock kerogen alkylpyrrole tetrapyrrole California. We’ll tell you more about this compound (cas:616-43-3).

C1-C6 alkylated pyrroles were identified as major constituents of the flash pyrolyzate of a kerogen from the Miocene Monterey Formation (California, USA) using gas chromatog. with an N-selective detector and gas chromatog.-mass spectrometry. The major alkylpyrroles identified are 2,3,4-trimethylpyrrole, 3-ethyl-4-methylpyrrole, 2,3-dimethyl-4-ethylpyrrole, 2,4-dimethyl-3-ethylpyrrole, and 3-ethyl-2,4,5-trimethylpyrrole. The alkyl substitution patterns of the alkylpyrroles strongly suggest an origin from tetrapyrrole pigments. Evidence for this hypothesis was provided by flash pyrolysis of the tetrapyrrole pigments chlorophyll-a, protoporphyrin-IX di-Me ester, and bilirubin, which yielded alkylpyrroles with a similar isomer distribution. Quant. pyrolysis using a polymer internal standard of both the kerogen and the tetrapyrrole pigments revealed that ca. 5% of the kerogen consists of macromolecularly bound tetrapyrrole pigments or that this fraction contains ca. 5% insoluble tetrapyrrole salts. These results show that in specific cases tetrapyrrole pigments can contribute significantly to the sedimentary organic matter.

Compound(616-43-3)Reference of 3-Methyl-1H-pyrrole received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(3-Methyl-1H-pyrrole), if you are interested, you can check out my other related articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Microchemical Journal called Analysis of metabolites and metabolic mechanism in Bt transgenic and non-transgenic maize, Author is Zhang, Liyuan; Yu, Runzhong; Yu, Yingbo, which mentions a compound: 3685-23-2, SMILESS is N[C@H]1CC[C@H](CC1)C(O)=O, Molecular C7H13NO2, Safety of cis-4-Aminocyclohexane carboxylic acid.

The gas chromatog.-mass spectrometry was used to isolate and identify metabolites of non-transgenic and Bacillus thuringiensis transgenic maize. The non-targeted metabolomics technique was used to anal. the metabolic pathway and mechanism of two kinds of maize. The methanol was used as extractant and the N,O-bis(trimethylsilyl) trifluoroacetamide was used as derivatization reagent. 38 kinds of metabolites were isolated and identified from non-transgenic maize, and 61 kinds of metabolites were isolated and identified in Bacillus thuringiensis transgenic maize. The specific metabolites between non-transgenic and Bacillus thuringiensis transgenic maize were analyzed. The metabolic pathway of specific metabolites was analyzed by KEGG annotation. The metabolic mechanism of non-transgenic maize and Bacillus thuringiensis transgenic maize was explored. The result indicated there were more metabolites involved in metabolic pathways in Bacillus thuringiensis transgenic maize than in non-transgenic maize, and tricarboxylic acid cycle and energy metabolism pathways of Bacillus thuringiensis transgenic maize are found to be higher than that of non-transgenic maize. The metabolic pathway of Bacillus thuringiensis transgenic maize conforms to the biol. activity law.

Compound(3685-23-2)Safety of cis-4-Aminocyclohexane carboxylic acid received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(cis-4-Aminocyclohexane carboxylic acid), if you are interested, you can check out my other related articles.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate