Electric Literature of 19132-06-0, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.19132-06-0, Name is (2S,3S)-Butane-2,3-diol, molecular formula is C4H10O2. In a article£¬once mentioned of 19132-06-0
Sequential Kinetic Resolution of (+/-)-2,3-Butanediol in Organic Solvent Using Lipase From Pseudomonas cepacia.
Lipase from Pseudomonas capacia (PCL, Amano PS) catalyzed the enantioselective diacetylation of (+/-)-2,3-butanediol in vinyl acetate.Both acetylation steps favored the (R)-enantiomer (E1 = 12, E2 = 34), thus the reaction is a sequential kinetic resolution.The enantioselectivities of the two steps reinforced one another because both steps proceeded at comparable rates (S = 3) yielding an overall enantioselectivity of approximately 200.A synthetic-scale resolution starting from 2.7 g of (+/-)-2,3-butanediol yielded the diacetate ester of (R)-(-)-butanediol with 96percent ee (1.6 g, 30percent yield) and (S)-(+)-butanediol with 99percent ee (0.63 g, 23percentyield).This preparation is carried out entirely in organic solvent, thereby avoiding the difficult and low yield extraction of 2,3-butanediol from aqueous solution.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 19132-06-0, help many people in the next few years.Electric Literature of 19132-06-0
Reference£º
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate