Synthetic Route of 24621-61-2, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 24621-61-2, (S)-Butane-1,3-diol, introducing its new discovery.
Chiral alpha,omega-Dioxy-Carbanions from 1,3-Propanediol and 1,4-Butanediol by Sparteine-Assisted Deprotonation. Enantioselective Synthesis of 1,3- and 1,4-Diols, (R)-Pantolactone, and a Cyclopropane
Prostereogenic mono- and dicarbamates of 1,3-propanediol and 1,4-butanediol are deprotonated by the sec-butyllithium/(-)-sparteine system with high enantiotopic differentiation.The electrophilic substitution of the intermediate chiral carbanions furnishes the title compounds with >95percent ee. Key words: Chiral 1-oxy-carbanions; enantioselective deprotonation; (-)-sparteine.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 24621-61-2. In my other articles, you can also check out more blogs about 24621-61-2
Reference£º
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate