Tag: M.W:200-300

538-58-9, An elementary termolecular reaction involves the simultaneous collision of three atoms, molecules, or ions.4254-15-3, name is (S)-Propane-1,2-diol. Here is a downstream synthesis route of the compound 4254-15-3

Bis(dibenzylideneacetone)palladium(0) (Pd(dba)2)was synthesized by reducing PdCl2 with methanol in thepresence of sodium acetate and dba [30]. Dibenzylideneacetone(3.4500 g, 1.472 ¡Á 10-2 mol), sodium acetatetrihydrate (4.8525 g, 3.568 ¡Á 10-2 mol), and methanol(113 mL) were placed in a two-neck round-bottomflask. The reaction mixture was stirred at 50C for 45-60 min to obtain a solution, and PdCl2 (0.7875 g,4.434 ¡Á 10-3 mol) was added. The resulting solutionwas stirred in an argon atmosphere at 40C for 4 h.This yielded a dark violet precipitate of the Pd(dba)2complex, which was collected on a fritted glass filterunder argon, washed with water and acetone, andvacuum-dried (30C/2-3 Torr) for 3 h. The productyield was 2.4 g. (94% of the theoretical yield); m =152C. According to the literature, m of thePd(dba)2 complex is 152C [31]. UV spectra:Pd(dba)2, 525 nm (d ? d* transition, epsilon525 =6400 L mol-1 cm-1); non-coordinated dba, 325 nm(n ? pi* transition, epsilon325 = 33540 L mol-1 cm-1).

This molecular description is the mechanism of the reaction; it describes how individual atoms, ions, or molecules interact to form particular products.If you are interested, you can also browse other articles of 1,5-Diphenylpenta-1,4-dien-3-one, We look forward to the emergence of more reaction modes in the future.

Reference£º
Article; Skripov; Belykh; Sterenchuk; Akimov; Tauson; Schmidt; Kinetics and Catalysis; vol. 58; 1; (2017); p. 34 – 45; Kinet. Katal.; vol. 58; 1; (2017); p. 36 – 48,13;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate

538-58-9, The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.538-58-9, name is 1,5-Diphenylpenta-1,4-dien-3-one. A new synthetic method of this compound is introduced below.

General procedure: 9-Amino(9-deoxy)-epi-quinine (6.5 mg, 0.02 mmol), divinyl ketone 1 (0.1 mmol), nitromethane (262 muL, 3.0 mmol), Proton-sponge (4.3 mg, 0.02 mmol) and benzoic acid (4.9 mg, 0.04 mmol) were dissolved in chlorobenzene (238muL). After stirred at 40 oC for 144 h, the reaction mixture was purified by flash chromatography on silica gel (EtOAc/petroleum ether).

Thank you very much for taking the time to read this article. If you are also interested in other aspects of 1,5-Diphenylpenta-1,4-dien-3-one, CAS: 538-58-9, you can also browse my other articles.

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Article; Yao, Yongqi; Liu, Yingying; Ye, Ling; Chen, Feng; Li, Xinying; Zhao, Zhigang; Li, Xuefeng; Tetrahedron; vol. 73; 16; (2017); p. 2311 – 2315;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate

One of the major reasons is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time, to discover the sequence of events that occur at the molecular level.538-58-9, 1,5-Diphenylpenta-1,4-dien-3-one, introduce a new downstream synthesis route. 538-58-9

General procedure: General procedure: A mixture of 8a (70.3 mg, 0.3 mmol) and 1a (172.2 mg, 0.36 mmol) in DMSO (2.0 mL) was stirred under nitrogen atmosphere for 5 min at room temperature. Then DBU (0.065 mL, 0.45 mmol), followed by DMSO (1 mL), was added and the resulting mixture was heated to 80 C in N2 atmosphere. After the reaction was complete, the mixture was filtered through a thin layer (30 mm) of silica gel (100-200 mesh) and washed with DCM. The filtrate was concentrated under reduced pressure and the residue was purified by flash chromatography (PE/EtOAc=60/1) to afford 11a (72.1 mg, 76%).

This molecular description is the mechanism of the reaction; it describes how individual atoms, ions, or molecules interact to form particular products.If you are interested, you can also browse other articles of 538-58-9, We look forward to the emergence of more reaction modes in the future.

Reference£º
Article; Shu, Zhen-Cao; Zhu, Jian-Bo; Liao, Saihu; Sun, Xiu-Li; Tang, Yong; Tetrahedron; vol. 69; 1; (2013); p. 284 – 292;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate

538-58-9, The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.538-58-9, name is 1,5-Diphenylpenta-1,4-dien-3-one. A new synthetic method of this compound is introduced below.

538-58-9, General procedure: A mixture of unsaturated ketone 1a (60.7 mg, 0.25 mmol) and phosphonium salt 2a (198.6 mg, 0.45 mmol) in CH3CN (2 mL) was stirred for 5 min. Then DBU (127 muL) in CH3CN (0.5 mL) was added. The reaction mixture was stirred at 60 C for 6 h and then air was introduced with a balloon for another 42 h. After the reaction was completed, the reaction mixture was filtered through a short silica gel column and washed with DCM. The filtrate was concentrated under reduced pressure and the residue was purified by flash chromatography (PE/EtOAc, 60/1) to afford 3a as a colorless oil (69.3 mg, 86% yield).

Thank you very much for taking the time to read this article. If you are also interested in other aspects of 1,5-Diphenylpenta-1,4-dien-3-one, CAS: 538-58-9, you can also browse my other articles.

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Article; Shu, Zhen-Cao; Zhu, Jian-Bo; Liao, Saihu; Sun, Xiu-Li; Tang, Yong; Tetrahedron; vol. 69; 1; (2013); p. 284 – 292;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate

The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.538-58-9, name is 1,5-Diphenylpenta-1,4-dien-3-one. A new synthetic method of this compound is introduced below. , 538-58-9

General procedure: A solution of N,N-dimethyl barbituric acid (1) (2 mmol) and diarylidene acetone derivatives (2a-p) (2 mmol) in 10 mL of dry CH2Cl2 were charged into a 50 mL round bottom flask under inert atmosphere. Et2NH (2.5 mmol) was then added to the reaction mixture and stirred at room temperature for up to 1.5-2 h, until TLC showed complete consumption of both the reactants. After completion of the reaction, the crude product was directly subjected to column chromatography, using 100-200 mesh silica gel and ethyl acetate/n-hexane (2:8, v/v) as an eluent to afford the pure products 3a-p. The solid products were further crystallized from a mixture of CHCl3/n-heptane. 4.2.1 2,4-Dimethyl-7,11-diphenyl-2,4-diazaspiro[5.5]undecane-1,3,5,9-tetraone (3a) Diarylidene acetone 2a (468.2 mg, 2 mmol) reacted with compound 1 (312.1 mg, 2 mmol) according to GP1 yielded white solid spiro-product 3a (765 mg, 1.96 mmol, 98%); mp 125-127 C; 1H NMR (400 MHz, CDCl3) delta: 2.59 and 2.63 (dd, 2H, J = 15.36 Hz, 4.40 Hz, CH2(e)), 2.85 (s, 3H, -NCH3), 3.01 (s, 3H, -NCH3), 3.72 (t, 2H, J = 14.7 Hz, CH2(a)), 3.99 and 4.03 (dd, 2H, J = 14.7 Hz, 4.40 Hz, CH), 7.06-7.08 (m, 4H, Ar-H), 7.21-7.26 (m, 6H, Ar-H); 13C NMR (100 MHz, CDCl3) delta: 27.98, 28.39, 42.99, 50.55, 60.95, 127.56, 128.69, 128.94, 137.17, 149.70, 169.04, 170.71, 208.29; IR (KBr, cm-1) numax = 2959, 2925, 1716, 1675, 1484, 1422, 1381, 1125, 755, 706; [Anal. Calcd for C23H22N2O4: C, 70.75; H, 5.68; N, 7.17; Found: C, 70.69; H, 5.65; N, 7.01]; LC/MS (ESI, m/z): [M+], calculated 390.21, C23H22N2O4 found 390.16; CCDC-1007513.

A chemical reaction often occurs in steps, although it may not always be obvious to an observer. Thank you very much for taking the time to read this article. If you are also interested in other aspects of 1,5-Diphenylpenta-1,4-dien-3-one, CAS: 538-58-9, you can also browse my other articles.

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Article; Barakat, Assem; Islam, Mohammad Shahidul; Al-Majid, Abdullah Mohammed; Ghabbour, Hazem A.; Fun, Hoong-Kun; Javed, Kulsoom; Imad, Rehan; Yousuf, Sammer; Choudhary, M. Iqbal; Wadood, Abdul; Bioorganic and Medicinal Chemistry; vol. 23; 20; (2015); p. 6740 – 6748;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate

The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.538-58-9, name is 1,5-Diphenylpenta-1,4-dien-3-one. A new synthetic method of this compound is introduced below. , 538-58-9

General procedure: General procedure: A mixture of 8a (70.3 mg, 0.3 mmol) and 1a (172.2 mg, 0.36 mmol) in DMSO (2.0 mL) was stirred under nitrogen atmosphere for 5 min at room temperature. Then DBU (0.065 mL, 0.45 mmol), followed by DMSO (1 mL), was added and the resulting mixture was heated to 80 C in N2 atmosphere. After the reaction was complete, the mixture was filtered through a thin layer (30 mm) of silica gel (100-200 mesh) and washed with DCM. The filtrate was concentrated under reduced pressure and the residue was purified by flash chromatography (PE/EtOAc=60/1) to afford 11a (72.1 mg, 76%).

A chemical reaction often occurs in steps, although it may not always be obvious to an observer. Thank you very much for taking the time to read this article. If you are also interested in other aspects of 1,5-Diphenylpenta-1,4-dien-3-one, CAS: 538-58-9, you can also browse my other articles.

Reference£º
Article; Shu, Zhen-Cao; Zhu, Jian-Bo; Liao, Saihu; Sun, Xiu-Li; Tang, Yong; Tetrahedron; vol. 69; 1; (2013); p. 284 – 292;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate

538-58-9, The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.538-58-9, name is 1,5-Diphenylpenta-1,4-dien-3-one. A new synthetic method of this compound is introduced below.

538-58-9, General procedure: In a general procedure, dibenzylidene acetone (1 mmol), N,N-dimethylbarbituric acid/barbituric acid/thiobarbituric acid(1 mmol) and 4 mL of ethanol:water (1:1) were taken in a 50 mL round-bottomed flask. 10 mol% of tetrabutyl ammonium bromide (TBAB) was added to the mixture, and the contents were stirred. The reaction mixture was refluxed and the progress of the reaction was monitored by TLC using ethyl acetate:petroleum ether (30:70) as eluent for disappearance of active methylene compounds. After completion of the reaction, the reaction mixture was allowed to cool to room temperature and diluted with water (5 mL). The solid obtained was filtered at pump and washed with water:ethanol (2:1). The product was recrystallized with ethanol. The products were characterized by their spectral data.

A chemical reaction often occurs in steps, although it may not always be obvious to an observer. Thank you very much for taking the time to read this article. If you are also interested in other aspects of 1,5-Diphenylpenta-1,4-dien-3-one, CAS: 538-58-9, you can also browse my other articles.

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Article; Aggarwal, Komal; Khurana, Jitender M.; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 143; (2015); p. 288 – 297;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate

538-58-9 A common heterocyclic compound, 538-58-9,1,5-Diphenylpenta-1,4-dien-3-one, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General procedure: A flask equipped a magnetic stirring bar was charged with alpha,beta-unsaturatedketone 1 (1.0 mmol), tosylhydrazine(1.1 mmol), K2CO3 (1.5 mmol),and dioxane (2 ml). The reaction mixture was stirredunder a nitrogen atmosphere at 110 Cfor 24 h. The reaction mixture was cooled to room temperature; the reaction mixture was extracted with diethylether (5¡Á3 ml). The combined extracts was washed withbrine and dried over MgSO4, and the crude product was adsorbed ontosilica gel and purified by column chromatography (silica gel, petroleum ether:ethyl acetate 20:1) gave the pure saturated carbonyl compound 4., 538-58-9

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand 538-58-9 reaction routes.

Reference£º
Article; Zhou, Xiaomeng; Li, Xiaokang; Zhang, Wei; Chen, Junmin; Tetrahedron Letters; vol. 55; 37; (2014); p. 5137 – 5140;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate

538-58-9,A common heterocyclic compound, 538-58-9,1,5-Diphenylpenta-1,4-dien-3-one, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General procedure: Method A: A mixture of appropriate derivatives of both 1,3-diaryl-2-propen-1-ones (1.0 equiv.) and aryl hydrazine (1.1 equiv.) was taken in a 100mL round-bottomed flask in 95% ethanol (25mL). Addition of a drop of H2SO4 initiated the precipitation. The reaction mixture was refluxed for 3 to 5h and cooled to room temperature to form precipitate in most of the cases. The residue was filtered, washed with water and dried under vacuum. In some cases where precipitate was not observed after cooling to room temperature, water was added to obtain precipitate.

The chemical industry reduces the impact on the environment during synthesis, 538-58-9,1,5-Diphenylpenta-1,4-dien-3-one,I believe this compound will play a more active role in future production and life.

Reference£º
Article; Ananthnag, Guddekoppa S.; Adhikari, Adithya; Balakrishna, Maravanji S.; Catalysis Communications; vol. 43; (2014); p. 240 – 243;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate

538-58-9,The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a downstream synthesis route of the compound 538-58-9

General procedure: A mixture of divinyl ketone (0.5 mmol), indolin-2-one (0.6 mmol)and cesium carbonate (0.5 mmol) in methylene chloride (5 mL) wasstirred at room temperature for the appropriate time. Then the resultingmixture was extracted with ethyl acetate (2 ¡Á 5 mL). The combinedorganic layers were dried over anhydrous magnesium sulfate andconcentrated under reduced pressure. The residues were isolated bycolumn chromatography using petroleum ether and ethyl acetate (v/v5 : 1) as eluent to give the pure product.2,6-Diphenylspiro[cyclohexane-1,3?-indoline]-2?,4-dione (2a): Whitesolid; m.p. 216-218 C; 1H NMR (600 MHz, CDCl3): delta 8.70 (s, 1H),7.23-7.20 (m, 3H), 7.00-6.95 (m, 6H), 6.90 (d, J = 7.3 Hz, 2H), 6.72 (t,J = 7.6 Hz, 1H), 6.56 (d, J = 7.7 Hz, 1H), 6.21 (d, J = 7.6 Hz, 1H), 3.96(t, J = 14.3 Hz, 1H), 3.80 (dd, J = 14.0, 3.7 Hz, 1H), 3.69 (t, J = 6.0 Hz,1H), 3.62 (dd, J = 16.1, 6.0 Hz, 1H), 2.99 (dd, J = 16.1, 5.9 Hz, 1H),2.72 (dd, J = 15.8, 3.4 Hz, 1H); 13C NMR (150 MHz, CDCl3): delta 211.4,180.9, 140.2, 139.9, 138.0, 130.0, 129.3, 128.2, 128.1, 128.0, 127.9,127.4, 127.2, 125.9, 121.4, 109.3, 56.0, 46.6, 45.5, 42.7, 41.9; Anal.calcd for C25H21NO2: C, 81.72; H, 5.76; N, 3.81; found: C, 81.66; H,5.78; N, 3.80%.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1,5-Diphenylpenta-1,4-dien-3-one.

Reference£º
Article; Li, Zheng; Li, Jiasheng; Yang, Jingya; Journal of Chemical Research; vol. 41; 3; (2017); p. 168 – 171;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate